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Can diabetics take Zyprexa?

Leia Doyle

Can diabetics take Zyprexa?

Zyprexa (olanzapine), which is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression), can cause high blood sugar (hyperglycemia). People who have diabetes need to check their blood sugar levels regularly while taking Zyprexa.

Can diabetics take olanzapine?

Olanzapine significantly increased the risk of diabetes compared with no antipsychotic (adjusted odds ratio 5.8 [95% CI 2.0–16.7]). The risk associated with risperidone was less (2.2 [0.9–5.2]). They also found a small increase in risk associated with conventional neuroleptics (1.4 [1.1–1.7]).

How does Olanzapine affect blood sugar?

Olanzapine-treated patients had a significantly greater increase in 1-hour glucose and insulin levels during OGTT in subsequent months compared to baseline and greater increase in glucose and insulin area under the curve over time than the risperdone-treated patients.

Can antipsychotics affect blood sugar?

Antipsychotics likely increase the risk of diabetes through weight gain and directly by adversely affecting insulin sensitivity and secretion.

Why does Zyprexa cause diabetes?

The exact cause of glucose dysregulation by olanzapine is not clear. It has been hypothesized that 5-HT1 antagonism may decrease the responsiveness of the pancreatic beta cells, thus reducing the secretion of insulin and causing hyperglycemia.

What are the side effects of Zyprexa?

Drowsiness, dizziness, lightheadedness, stomach upset, dry mouth, constipation, increased appetite, or weight gain may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling.

Why is olanzapine contraindicated in diabetes?

Does olanzapine cause low blood sugar?

DISCUSSION: Olanzapine is a commonly used atypical antipsychotic medication. It has well documented side effects of dyslipidemia and hyperglycemia, often resulting in new onset diabetes in patients. However, there are very rare reported cases of hypoglycemia with this medication.

What happens if you drink alcohol with olanzapine?

You can continue to drink some alcohol while taking olanzapine, but having the two together might make you very sleepy or make you fall over. If you drink a lot of alcohol, these effects will be much more serious. Alcohol can also make the symptoms of your condition worse.

Which antipsychotic has least side effects?

Aripiprazole had less side- effects than olanzapine and risperidone (such as weight gain, sleepiness, heart problems, shaking and increased cholesterol levels).

Does Zyprexa raise cholesterol?

Eli Lilly yesterday added strong warnings to the label of Zyprexa, its best-selling medicine for schizophrenia, citing the drug’s tendency to cause weight gain, high blood sugar, high cholesterol and other metabolic problems.

How strong is Zyprexa?

The oral dose usually ranges from 5 mg to 20 mg. The dose of the injection usually ranges from 150 mg to 405 mg. Only your healthcare provider can determine the correct dose for you. Olanzapine orally disintegrating tablets must remain in their original packaging.

Is 10 mg of Zyprexa a lot?

For treatment of mania or mixed episodes with bipolar disorder (olanzapine alone): Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose if needed. However, the dose is usually not more than 20 mg per day.

Is Zyprexa a good drug?

Zyprexa has an average rating of 6.1 out of 10 from a total of 277 ratings on Drugs.com. 49% of users who reviewed this medication reported a positive effect, while 29% reported a negative effect.

What contraindications are associated with olanzapine?

The following conditions are contraindicated with this drug….Who should not take OLANZAPINE?

  • breast cancer.
  • diabetes.
  • a high prolactin level.
  • high cholesterol.
  • high amount of triglyceride in the blood.
  • dehydration.
  • overweight.
  • low levels of white blood cells.

How do you know if Zyprexa is working?

When olanzapine is working well, you may notice that your thoughts are clearer and more organized. Agitation may be decreased and hearing voices or seeing things no one else sees (hallucinations) may stop completely or happen much less.

Does olanzapine calm you down?

Olanzapine gave me that opportunity in a way; it gave me peace for the first time in months. It didn’t stop the pain or the anxiety, but it gave me the ability to rest, sleep, and relax.

Does olanzapine slow down your metabolism?

Indeed, reduced body temperature after olanzapine treatment may generate many of the known side effects of this antipsychotic drug. The authors’ new findings also demonstrate that olanzapine alters peripheral glucose metabolism, which may contribute to impaired insulin sensitivity.