How do you get SIRTURO?

How do you get SIRTURO?

SIRTURO® is available by prescription from healthcare professionals associated with qualified centers for the evaluation, diagnoses, and treatment of TB, including pulmonary MDR-TB. Qualified centers include public health departments, clinics that treat TB, and hospitals and institutions with a TB concentration.

Who makes SIRTURO?

TITUSVILLE, NJ, August 9, 2019 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for SIRTURO® (bedaquiline) tablets as part of combination therapy in pediatric patients – those over the age of 12 and younger than 18 and …

How much does Bedaquiline cost?

The Union welcomes the announcement that bedaquiline will be made available to Stop TB Partnership’s Global Drug Facility at a price of USD$340 per six-month treatment course for more than 135 eligible low- and middle-income countries.

Who makes Bedaquiline?

SIRTURO® (bedaquiline) | Official Website | About SIRTURO.

Who makes clofazimine?

Clofazimine is marketed under the trade name Lamprene by Novartis.

Where was Pretomanid developed?

Pretomanid is referred to as “Pa” in regimen abbreviations, such as BPaL. The “preto” prefix of the compound’s name honors Pretoria, South Africa, the home of a TB Alliance clinical development office where much of the drug’s development took place.

What are the side effects of bedaquiline?

Common side effects of Sirturo include:

  • nausea.
  • joint pain.
  • headache.
  • coughing up blood.
  • chest pain.
  • weight loss.
  • rash.
  • increased transaminases and blood amylase.

Is Delamanid FDA approved?

Unlike the two other new drugs in the TB arsenal, bedaquiline and delamanid, pretomanid is the first FDA-approved TB drug to be developed and registered by a non-profit organisation, the TB Alliance.

What are the side effects of Bedaquiline?

What is the treatment of MDR TB?

MDR regimens should include at least pyrazinamide, a fluoroquinolone, an injectable anti-TB drug, ethionamide (or prothionamide) and either cycloserine or PAS (para-aminosalycylic acid) if cycloserine cannot be used (conditional recommendation, very low quality evidence)(1).

Is bedaquiline an antibiotic?

For example, bedaquiline is an antibiotic recently developed to treat tuberculosis infections that are resistant to several drugs.

What are the side effects of taking clofazimine?

COMMON side effects

  • discoloration of the eyelid.
  • tear discoloration.
  • irritation of the stomach or intestines.
  • itching.
  • discolored sweat.
  • a skin rash.
  • decreased appetite.
  • sputum discoloration.